彼得与狼钢琴曲:在线等。。药学英语翻译,望求高手帮忙!!

来源:百度文库 编辑:查人人中国名人网 时间:2024/04/28 20:50:15
Peak blood levels are reached within one hour after oral administration of cetirizine.The plasma half-life is approximately 10 hours in adults, 6 hours in children aged 6 to 12 years and 5 hours in children aged 2 to 6 years. These data are consistent with the urinary excretion half-life of the drug.The cumulative urinary excretion represents about two thirds of the dose given in both adults and children. Consequently, the apparent plasma clearance in children is higher than that measured in adults.
Absorption is very consistent from one subject to the next.
Plasma levels are linearly reated to the dose given.
Cetirizine is strongly bound to plasma proteins.

在口服西替利嗪一小时后药物达到血液峰浓度。在血浆中的排泄半衰期,成人为10小时,6到12岁儿童为6小时,2到6岁儿童为5小时。这些数据与药物的泌尿排泄半衰期一致。累积的泌尿排泄剂量占药物总摄入量的三分之二,在成人及儿童中均一样。药品在血浆中清除的速度,在儿童中要比在成人中快。受试者的吸收情况均非常一致。药品的血液浓度与射入剂量呈线性关系。西替利嗪与血样中的蛋白结合很紧密。

高峰血水平达到一个小时后,在口腔等离子管理下。半衰期约为10小时,成人6小时6至12岁的儿童和5年时间在2岁的孩子到6岁. 这些数据与泌尿排泄半衰期有关。成年人和儿童累积的排泄物泌尿约占三分之二的剂量. 因此,等离子表面清理儿童高于成人衡量. 承担课题之一是非常一致的作法. 等离子体的水平直线剂量给予有关.